Physical Properties and Cellular Metabolic Characteristics of 3D Spheroids Are Possible Definitive Indices for the Biological Nature of Cancer-Associated Fibroblasts

The current study’s objective was to elucidate some currently unknown biological indicators to evaluate the biological nature of cancer-associated fibroblasts (CAFs). For this purpose, four different CAFs, CAFS1, CAFS2, SCC17F and MO-1000, were established using surgical specimens from oral squamous...

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Bibliographic Details

Published in:	Cells
Main Authors:	Nami Nishikiori, Kohichi Takada, Tatsuya Sato, Sho Miyamoto, Megumi Watanabe, Yui Hirakawa, Shohei Sekiguchi, Masato Furuhashi, Akira Yorozu, Kenichi Takano, Akihiro Miyazaki, Hiromu Suzuki, Hiroshi Ohguro
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Subjects:	cancer-associated fibroblast 3D spheroid culture oral squamous carcinoma Seahorse bioanalyzer
Online Access:	https://www.mdpi.com/2073-4409/12/17/2160