Sex differences in the outcomes of modifiable lifestyle factors for cognitive aging: neuroinflammation and microglia as key underlying mechanisms

Microglia are the resident immune cells of the brain. Over the past two decades, they have been shown to play critical roles throughout life. Microglia are now considered to be important for brain formation, maturation, activity and plasticity, with outcomes on behavior and other cognitive domains....

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Bibliographic Details

Published in:	Frontiers in Aging Neuroscience
Main Authors:	Samantha G. Coleborn, Zoë M. Gilson, Yunyong Guo, Marie-Ève Tremblay
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	microglia cognitive aging sex differences diet exercise social isolation
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1642043/full