Biomarker Genes Discovery of Alzheimer’s Disease by Multi-Omics-Based Gene Regulatory Network Construction of Microglia

Microglia, the major immune cells in the brain, mediate neuroinflammation, increased oxidative stress, and impaired neurotransmission in Alzheimer’s disease (AD), in which most AD risk genes are highly expressed. In microglia, due to the limitations of current single-omics data analysis, risk genes,...

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Bibliographic Details

Published in:	Brain Sciences
Main Authors:	Wenliang Gao, Wei Kong, Shuaiqun Wang, Gen Wen, Yaling Yu
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	SCENIC multi-omics gene regulatory network microglia prognosis immunotherapy
Online Access:	https://www.mdpi.com/2076-3425/12/9/1196