Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1

Summary: The game between therapeutic monoclonal antibodies (mAbs) and continuously emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has favored the virus, as most therapeutic mAbs have been evaded. Addressing this challenge, we systematically explored a reproducible bi...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Zhou Tong, Jianyu Tong, Wenwen Lei, Yufeng Xie, Yingzi Cui, Guowen Jia, Shihua Li, Zezhong Zhang, Zhimin Cheng, Xiao Xing, Haiyun Ma, Lan Deng, Rong Zhang, Xin Zhao, Kefang Liu, Qihui Wang, Jianxun Qi, Haomin Huang, Rui Song, Zhaoming Su, Guizhen Wu, Jing Lou, George Fu Gao
Format: Article
Language:English
Published: Elsevier 2024-06-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724006661