Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells

Cystic fibrosis (CF) is the most common lethal inherited disorder and is caused by mutations in the gene encoding the CF transmembrane regulator (CFTR). The CF lung expresses a profound proinflammatory phenotype that appears to be related to a constitutive hypersecretion of interleukin (IL)-8 from a...

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Bibliographic Details

Published in:	Journal of Pharmacological Sciences
Main Authors:	Shota Mizunoe, Tsuyoshi Shuto, Shingo Suzuki, Chizuru Matsumoto, Kenji Watanabe, Keiko Ueno-Shuto, Mary Ann Suico, Kouhei Onuki, Dieter C. Gruenert, Hirofumi Kai
Format:	Article
Language:	English
Published:	Elsevier 2012-01-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319305456