Effect of remote ischemic postconditioning on hepatic ischemia–reperfusion injury in patients undergoing laparoscopic hepatectomy: a randomized double-blinded controlled trial

BackgroundHepatic ischemia–reperfusion injury (HIRI) remains a major determinant of outcomes after hepatectomy with hepatic portal occlusion. Animal studies suggest that remote ischemic postconditioning (RIPostC) could alleviate HIRI, but its clinical value is unclear. This trial aimed to evaluate t...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Chao Yang, Lijun Yang, Mingwang Zeng, Yunyan Zhu, Chuanwu Zhang, Jing Chen, Yi Wang, Jinji Peng, Li-feng Wang, Maolin Zhong, Haiyu Xie, Weidong Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	remote ischemic postconditioning hepatectomy ischemia–reperfusion injury liver function laparoscopic surgery
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1628781/full