Recipient Tregs: Can They Be Exploited for Successful Hematopoietic Stem Cell Transplant Outcomes?

Human and mouse CD4+FoxP3+ T cells (Tregs) comprise non-redundant regulatory compartments which maintain self-tolerance and have been found to be of potential therapeutic usefulness in autoimmune disorders and transplants including allogeneic hematopoietic stem cell transplantation (allo-HSCT). Ther...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Sabrina N. Copsel, Dietlinde Wolf, Brent Pfeiffer, Henry Barreras, Victor L. Perez, Robert B. Levy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Subjects:	Tregs GvHD HSCT = hematopoietic stem cell transplant recipient tregs treatment
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.932527/full