Mechanical, optical, and physicochemical properties of HPMC-based doxazosin mesylate orodispersible films

Abstract In this study, orodispersible films formed from hydroxypropyl methylcellulose (HPMC) E6 (2, 2.5, and 3%) and plasticizers ((glycerin (Gly), propylene glycol (PP), or polyethylene glycol (PEG)), containing doxazosin mesylate, were prepared by the solvent casting method and characterized. Des...

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Bibliographic Details

Published in:	Brazilian Journal of Pharmaceutical Sciences
Main Authors:	Pamela Coradi da Silva, Larissa Aroca Colucci, Larissa Lea da Silva, Celso Molina, Marcelo Dutra Duque, Leticia Norma Carpentieri Rodrigues
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2023-04-01
Subjects:	Orodispersible films Design of experiments Doxazosin mesylate FTIR Mechanical properties Desirability function
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100319&tlng=en