NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy.

Muscular dystrophies are common, currently incurable diseases. A subset of dystrophies result from genetic disruptions in complexes that attach muscle fibers to their surrounding extracellular matrix microenvironment. Cell-matrix adhesions are exquisite sensors of physiological conditions and mediat...

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Bibliographic Details
Published in:PLoS Biology
Main Authors: Michelle F Goody, Meghan W Kelly, Christine J Reynolds, Andre Khalil, Bryan D Crawford, Clarissa A Henry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001409&type=printable