Sirtuin 1 and Autophagy Attenuate Cisplatin-Induced Hair Cell Death in the Mouse Cochlea and Zebrafish Lateral Line

Cisplatin-induced ototoxicity is one of the major adverse effects in cisplatin chemotherapy, and hearing protective approaches are unavailable in clinical practice. Recent work unveiled a critical role of autophagy in cell survival in various types of hearing loss. Since the excessive activation of...

詳細記述

書誌詳細

出版年:	Frontiers in Cellular Neuroscience
主要な著者:	Jiaqi Pang, Hao Xiong, Ting Zhan, Gui Cheng, Haiying Jia, Yongyi Ye, Zhongwu Su, Hongyu Chen, Hanqing Lin, Lan Lai, Yongkang Ou, Yaodong Xu, Suijun Chen, Qiuhong Huang, Maojin Liang, Yuexin Cai, Xueyuan Zhang, Xiaoding Xu, Yiqing Zheng, Haidi Yang
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2019-01-01
主題:	SIRT1 autophagy cisplatin cell death ototoxicity
オンライン･アクセス:	https://www.frontiersin.org/article/10.3389/fncel.2018.00515/full