Ruscogenin Mainly Inhibits Nuclear Factor-κB but Not Akt and Mitogen-Activated Protein Kinase Signaling Pathways in Human Umbilical Vein Endothelial Cells

Our previous results suggested that ruscogenin inhibited tumor necrosis factorα (TNF-α)–induced leukocyte adhesion, which correlated with its suppression of intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells. In the present studies, we further examined its effects on the main...

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Bibliographic Details
Published in:Journal of Pharmacological Sciences
Main Authors: Jiaxi Song, Junping Kou, Yalin Huang, Boyang Yu
Format: Article
Language:English
Published: Elsevier 2010-01-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319309090