[6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice

Although oxaliplatin is a well-known anti-cancer agent used for the treatment of colorectal cancer, treated patients often experience acute cold and mechanical allodynia as side effects. Unfortunately, no optimal treatment has been developed yet. In this study, [6]-shogaol (10 mg/kg, i.p.), which is...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Suyong Kim, Juan Gang, Ji-Hwan Lee, Hyejin Yang, Chunhoo Cheon, Seong-Gyu Ko, Hyunsu Bae, Woojin Kim
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Subjects:	[6]-shogaol GABA neuropathic pain oxaliplatin serotonin <i>Zingiber officinale</i> roscoe
Online Access:	https://www.mdpi.com/1424-8247/15/6/726