The roles of Cryptochrome-1: the circadian clock as a control point in cancer therapy

Abstract In this review, we carefully describe the composition and operation of cryptochrome-1 (CRY1). We introduce four related signaling pathways, namely cAMP/PKA/CREB signaling way, HIFα signaling way, NF-κB signaling way, STAT3 signaling way, FOXO signaling pathway and Hedgehog (HH) signaling pa...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Yijia Liu, Yanzhe Huang, Hongliang Luo, Xueqin Lin
Format: Article
Language:English
Published: BMC 2025-06-01
Subjects:
CRY1
Circadian clock
Cancer
Signaling pathway
In Silico
Online Access:https://doi.org/10.1186/s12967-025-06702-0

Internet

https://doi.org/10.1186/s12967-025-06702-0

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