Effect of HPMC and mannitol on drug release and bioadhesion behavior of buccal discs of buspirone hydrochloride: In-vitro and in-vivo pharmacokinetic studies

Abstract Delivery of orally compromised therapeutic drug molecules to the systemic circulation via buccal route has gained a significant interest in recent past. Bioadhesive polymers play a major role in designing such buccal dosage forms, as they help in adhesion of designed delivery system to muco...

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Bibliographic Details
Published in:Saudi Pharmaceutical Journal
Main Authors: A. Jaipal, M.M. Pandey, S.Y. Charde, P.P. Raut, K.V. Prasanth, R.G. Prasad
Format: Article
Language:English
Published: Springer 2014-12-01
Subjects:
Online Access:https://doi.org/10.1016/j.jsps.2014.11.012