Neoadjuvant therapy-induced immune dynamics and myeloid-associated resistance in advanced head and neck cancer

Abstract Understanding the dynamics of the tumor-immune ecosystem is crucial for advancing neoadjuvant strategies in cancer treatment. This study investigated alterations in the tumor-immune microenvironment related to the response to preoperative combination therapy with paclitaxel, carboplatin, an...

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Bibliographic Details

Published in:	npj Precision Oncology
Main Authors:	Alisa Kimura, Junichi Mitsuda, Kanako Yoshimura, Sumiyo Saburi, Nanako Murakami, Nana Sakurai, Koichi Yoshizawa, Hiroki Morimoto, Shigeyuki Mukudai, Hikaru Nagao, Hiroshi Ogi, Saya Shibata, Aya Miyagawa-Hayashino, Eiichi Konishi, Kyoko Itoh, Shigeru Hirano, Takahiro Tsujikawa
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Online Access:	https://doi.org/10.1038/s41698-025-00954-1