Activation of mTORC1 signaling in gastric X/A-like cells induces spontaneous pancreatic fibrosis and derangement of glucose metabolism by reducing ghrelin productionResearch in context

Background: Pancreatic fibrosis is a pathophysiological process associated with excessive deposition of extracellular matrix in pancreas, leading to reduced insulin secretion and derangement of glucose metabolism. X/A-like cells, a group of unique endocrine cells in gastric oxyntic mucosa, produce a...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Ruili Yu, Ziru Li, Shiying Liu, Bahetiyaer Huwatibieke, Yin Li, Yue Yin, Weizhen Zhang
Format:	Article
Language:	English
Published:	Elsevier 2018-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396418303852