Overcoming the Drawbacks of Sulpiride by Means of New Crystal Forms

This study aims at developing new multicomponent crystal forms of sulpiride, an antipsychotic drug. The main goal was to improve its solubility since it belongs to class IV of the BCS. Nine new adducts were obtained by combining the active pharmaceutical ingredient with acid coformers: a salt cocrys...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Pharmaceutics
المؤلفون الرئيسيون:	Rebecca Birolo, Federica Bravetti, Simone Bordignon, Ilenia D’Abbrunzo, Paolo P. Mazzeo, Beatrice Perissutti, Alessia Bacchi, Michele R. Chierotti, Roberto Gobetto
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2022-08-01
الموضوعات:	sulpiride improved solubility crystal engineering solid-state NMR X-ray diffraction molecular salts
الوصول للمادة أونلاين:	https://www.mdpi.com/1999-4923/14/9/1754