Effectiveness and safety of lubiprostone after switching from stimulant laxatives in elderly patients with chronic constipation

Abstract Background and Aim Stimulant laxatives may cause electrolyte abnormalities, dehydration, and abdominal pain; their long‐term use can lead to tolerance and subsequent refractory constipation. We investigated the effectiveness, safety, and quality of life after switching from stimulant laxati...

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Bibliographic Details

Published in:	JGH Open
Main Authors:	Masaki Maruyama, Suguru Miida, Toshihiro Sato, Takazumi Kimura, Azuma Watanabe, Hideo Watanabe, Masafumi Nishizawa, Kyohei Horikawa, Takahiro Kajiwara, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Shuji Terai
Format:	Article
Language:	English
Published:	Wiley 2023-09-01
Subjects:	constipation drug therapy elderly laxatives lubiprostone
Online Access:	https://doi.org/10.1002/jgh3.12956