Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we show that Smc5/6 is chromatin associated in unchall...

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Bibliographic Details

Published in:	eLife
Main Authors:	Thomas J Etheridge, Desiree Villahermosa, Eduard Campillo-Funollet, Alex David Herbert, Anja Irmisch, Adam T Watson, Hung Q Dang, Mark A Osborne, Antony W Oliver, Antony M Carr, Johanne M Murray
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2021-04-01
Subjects:	SMC proteins single-molecule microscopy DNA repair
Online Access:	https://elifesciences.org/articles/68579