Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids

Varicella-zoster virus (VZV) encephalitis and meningitis are potential central nervous system (CNS) complications following primary VZV infection or reactivation. With Type-I interferon (IFN) signalling being an important first line cellular defence mechanism against VZV infection by the peripheral...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jonas Govaerts, Elise Van Breedam, Sarah De Beuckeleer, Charlotte Goethals, Claudio Peter D’Incal, Julia Di Stefano, Siebe Van Calster, Tamariche Buyle-Huybrecht, Marlies Boeren, Hans De Reu, Søren R. Paludan, Marc Thiry, Marielle Lebrun, Catherine Sadzot-Delvaux, Helena Motaln, Boris Rogelj, Johan Van Weyenbergh, Winnok H. De Vos, Wim Vanden Berghe, Benson Ogunjimi, Peter Delputte, Peter Ponsaerts
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	human iPSc neurospheroids varicella-zoster virus type-I interferon signalling antigen presentation stress granules
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1458967/full