Epidemiology of cryptococcal meningitis and fluconazole heteroresistance in Cryptococcus neoformans isolates from a teaching hospital in southwestern China

ABSTRACT Cryptococcal meningitis (CM), a common and serious opportunistic infection mostly caused by Cryptococcus neoformans, is primarily treated with fluconazole. Nevertheless, Cryptococcus neoformans strains that undergo repeated exposure to azoles can gradually acquire heteroresistance to flucon...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Yunfei Huang, Yongqi Zhang, Shuangshuang Yang, Hongling Lu, Hanbing Yu, Xingyue Wang, Xiaojiong Jia, Dijiao Tang, Linhong Wu, Shifeng Huang, Ping Yang
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-08-01
Subjects:	cryptococcal meningitis Cryptococcus neoformans fluconazole heteroresistance antifungal susceptibility
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00725-24