Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream

Named after the two-faced Roman god of doorways, Janus kinases (JAKs) represent a class of tyrosine kinases. The JAK signaling pathway is pivotal for the downstream signaling of inflammatory cytokines, including interleukins, interferons, and multiple growth factors. This article provides an overvie...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Paul Smith, Wenqing Yao, Stacey Shepard, Maryanne Covington, Jim Lee, Jennifer Lofland, Ahmad Naim, Trupti Sheth, Bhavnish Parikh, Swamy Yeleswaram
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Subjects:	Janus kinase inflammation atopic dermatitis vitiligo topical
Online Access:	https://www.mdpi.com/1999-4923/13/7/1044