Lack of evidence for a role of anthrax toxin receptors as surface receptors for collagen VI and for its cleaved-off C5 domain/endotrophin

Summary: The microfibril-forming collagen VI is proteolytically cleaved and it was proposed that the released C-terminal Kunitz domain (C5) of the α3 chain is an adipokine important for tumor progression and fibrosis. Designated “endotrophin,” C5 is a potent biomarker for fibroinflammatory diseases....

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Bibliographic Details

Published in:	iScience
Main Authors:	Matthias Przyklenk, Stefanie Elisabeth Heumüller, Carolin Freiburg, Steffen Lütke, Gerhard Sengle, Manuel Koch, Mats Paulsson, Alvise Schiavinato, Raimund Wagener
Format:	Article
Language:	English
Published:	Elsevier 2022-10-01
Subjects:	Cell biology functional aspects of cell biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004222013888