Prognostic and predictive value of human equilibrative nucleoside transporter 1 (hENT1) in extrahepatic cholangiocarcinoma: a translational study

Introduction: Effective (neo) adjuvant chemotherapy for cholangiocarcinoma is lacking due to chemoresistance and the absence of predictive biomarkers. Human equilibrative nucleoside transporter 1 (hENT1) has been described as a potential prognostic and predictive biomarker. In this study, the potent...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Lenka N. C. Boyd, Lynn E. Nooijen, Mahsoem Ali, Jisce R. Puik, Jasmine Moustaquim, Stephanie M. Fraga Rodrigues, Robert Broos, Ali Belkouz, Laura L. Meijer, Tessa Y. S. Le Large, Joris I. Erdmann, Gerrit K. J. Hooijer, Michal Heger, Hanneke W. M. Van Laarhoven, Eva Roos, Geert Kazemier, Elisa Giovannetti, Joanne Verheij, Heinz-Josef Klümpen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	hENT1 cholangiocarcinoma perihilar cholangiocarcinoma distal cholangiocarcinoma extrahepatic cholangiocarcinoma prognostic biomarker
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1274692/full