Substrate stiffness and pressure alter retinal Müller glia response and extracellular matrix production

Background: The retina is highly influenced by its mechanical environment, with Müller glia (MG) acting as key mechanosensors and extracellular matrix (ECM) producers. This study examined MG responses to substrate stiffness and high pressure (HP), and whether TGF-β1 modulation could mitigate these e...

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Bibliographic Details

Published in:	Biomaterials and Biosystems
Main Authors:	Laura Prieto-López, Xandra Pereiro, Emilio J. González Ramírez, Noelia Ruzafa, Alicia Alonso, Kristian Franze, Elena Vecino
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	Müller glia Extracellular matrix Polyacrylamide gels Stiffness Pressure TGF-β1
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666534425000091