iPSCs and iPSC-derived cells as a model of human genetic and epigenetic variation

Abstract Understanding the interaction between genetic and epigenetic variation remains a challenge due to confounding environmental factors. We propose that human induced Pluripotent Stem Cells (iPSCs) are an excellent model to study the relationship between genetic and epigenetic variation while c...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Kara Quaid, Xiaoyun Xing, Yi-Hsien Chen, Yong Miao, Amber Neilson, Vijayalingam Selvamani, Aaron Tran, Xiaoxia Cui, Ming Hu, Ting Wang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-02-01
Online Access:	https://doi.org/10.1038/s41467-025-56569-4