Influence of Soft and Stiff Matrices on Cytotoxicity in Gingival Fibroblasts: Implications for Soft Tissue Biocompatibility

The biocompatibility of dental materials is critical for ensuring safety in clinical applications. However, standard in vitro cytotoxicity assays often rely on stiff tissue culture plastic (TCP), which does not accurately replicate the biomechanical properties of soft oral tissues. In this study, we...

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Bibliographic Details

Published in:	Cells
Main Authors:	Ye-Jin Yang, Donghyeon Yeo, Seong-Jin Shin, Jun Hee Lee, Jung-Hwan Lee
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Subjects:	human gingival fibroblasts substrate stiffness methyl methacrylate cytotoxicity biocompatibility assessment
Online Access:	https://www.mdpi.com/2073-4409/13/23/1932