Single-cell transcriptomic analysis reveals a decrease in the frequency of macrophage-RGS1high subsets in patients with osteoarticular tuberculosis

Abstract Background Cell subsets differentially modulate host immune responses to Mycobacterium tuberculosis (MTB) infection. However, the nature and functions of these subsets against osteoarticular tuberculosis (OTB) are unclear. Here, we aimed to understand the phenotypes and functions of immune...

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發表在:	Molecular Medicine
Main Authors:	Ying Jiang, Xinqiang Zhang, Bo Wang, Liping Tang, Xin Liu, Xiudong Ding, Yueming Dong, Hong Lei, Di Wang, Huicheng Feng
格式:	Article
語言:	英语
出版:	BMC 2024-08-01
主題:	Osteoarticular tuberculosis scRNA Biomarker Macrophages Ferroptosis
在線閱讀:	https://doi.org/10.1186/s10020-024-00886-9