A prognostic model of drug tolerant persister-related genes in lung adenocarcinoma based on single cell and bulk RNA sequencing data

Background: Acquired resistance to targeted drugs is a major challenge in cancer. The drug-tolerant state has been proposed to be an initial step towards acquisition of real drug-resistance. Drug tolerant persister (DTP) cells are purported to survive during treatment and stay dormant for several ye...

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書誌詳細

出版年:	Heliyon
主要な著者:	Zhonghai Du, Tongtong Zhang, Yanke Lin, Guifen Dong, Aixiang Li, Zhiqiang Wang, Yongjie Zhang, Georgios Giamas, Justin Stebbing, Liping Zhu, Ling Peng
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-11-01
主題:	Drug tolerant persister Non-small cell lung cancer Epidermal growth factor receptor Tyrosine kinase inhibitor Single-cell RNA sequencing Bulk RNA sequencing
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2405844023079161