Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus.

<h4>Background</h4>Vaccinia viruses have been used as a model for viral disease and as a protective live vaccine.<h4>Methodology and principal findings</h4>We investigated the immunogenicity of an attenuated strain of vaccinia virus engineered to inactivate the N1L gene (vGK5...

詳細記述

書誌詳細
出版年:PLoS ONE
主要な著者: Anuja Mathew, Joel O'Bryan, William Marshall, Girish J Kotwal, Masanori Terajima, Sharone Green, Alan L Rothman, Francis A Ennis
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2008-10-01
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003323&type=printable