Current Methods and Pipelines for Image-Based Quantitation of Nuclear Shape and Nuclear Envelope Abnormalities

Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity. Deviations from this can be indicative of diseases such as cancer or premature aging syndrome. To accurately assess nuclear abnormalities, it...

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Bibliographic Details

Published in:	Cells
Main Authors:	Anne F. J. Janssen, Sophia Y. Breusegem, Delphine Larrieu
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	nuclear envelope nuclear envelope abnormality lamina nuclear morphology
Online Access:	https://www.mdpi.com/2073-4409/11/3/347