Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism

Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying probiotics-driven drug metabolism. We discovered...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Bohai Li, Lai-Yu Kwok, Dandan Wang, Lu Li, Shuai Guo, Yongfu Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	drug metabolism probiotics metabolomics culturomics bionics
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1047863/full