Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition

The imbalance of bone homeostasis is the root cause of osteoporosis. However current therapeutic approaches mainly focus on either anabolic or catabolic pathways, which often fail to turn the imbalanced bone metabolism around. Herein we reported that a SIRT-1 agonist mediated molecular therapeutic s...

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发表在:	Bioactive Materials
Main Authors:	Wei Zhang, Xingzhi Zhou, Weiduo Hou, Erman Chen, Chenyi Ye, Mo Chen, Qian Lu, Xiaohua Yu, Weixu Li
格式:	文件
语言:	英语
出版:	KeAi Communications Co., Ltd. 2023-01-01
主题:	Osteoporosis Osteoblast Osteoclast Mineral coating SIRT1
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2452199X22001864