Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model

Abstract Several lines of evidence suggest that neuregulin 1 (NRG1) signaling may influence cognitive function and neuropathology in Alzheimer’s disease (AD). To test this possibility, full-length type I or type III NRG1 was overexpressed via lentiviral vectors in the hippocampus of line 41 AD mouse...

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出版年:	Scientific Reports
主要な著者:	Jiqing Xu, Fred de Winter, Catherine Farrokhi, Edward Rockenstein, Michael Mante, Anthony Adame, Jonathan Cook, Xin Jin, Eliezer Masliah, Kuo-Fen Lee
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2016-08-01
オンライン･アクセス:	https://doi.org/10.1038/srep31692