THBS1 in macrophage-derived exosomes exacerbates cerebral ischemia–reperfusion injury by inducing ferroptosis in endothelial cells

Abstract Macrophages play a critical role in the development of acute ischemic stroke (AIS). Cerebral ischemia–reperfusion injury (CIRI) is a pivotal pathological process that exacerbates AIS, with exosomes act as crucial mediators. However, the effects and mechanisms of action of macrophage-derived...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Journal of Neuroinflammation
المؤلفون الرئيسيون: Chang Liu, Haijing Sui, Zhixi Li, Zhenyu Sun, Chenglong Li, Guangmin Chen, Zhaoxue Ma, Hang Cao, Hongjie Xi
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2025-02-01
الموضوعات:
Ischemic stroke
Cerebral ischemia–reperfusion injury
Macrophage
Endothelial cells
Exosomes
الوصول للمادة أونلاين:https://doi.org/10.1186/s12974-025-03382-x

الانترنت

https://doi.org/10.1186/s12974-025-03382-x

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