DSPE-PEG Modification of α-Conotoxin TxID
In order to improve stability of a peptide marine drug lead, α-conotoxin TxID, we synthesized and modified TxID at the N-terminal with DSPE-PEG-NHS by a nucleophilic substitution reaction to prepare the DSPE-PEG-TxID for the first time. The reaction conditions, including solvent, ratio, pH,...
| Published in: | Marine Drugs |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-06-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/17/6/342 |