Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer

Ovarian cancer (OC) is a heterogeneous tumor entity with accumulated ascitic fluid in the peritoneal cavity, especially in advanced tumors. In general, a high immune cell infiltration has a favorable effect on OC patients’ outcomes. However, the composition of immune cells within the individual comp...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Rebecca Rothe, Antje Tunger, Theresa Link, Xixi Lai, Jan Dominik Kuhlmann, Pauline Wimberger, Marc Schmitz, Rebekka Wehner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	gynecologic cancer immunological biomarker immunophenotyping liquid biopsy local and peripheral immune system tumor microenvironment
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607471/full