Calreticulin Regulates SARS-CoV-2 Spike Protein Turnover and Modulates SARS-CoV-2 Infectivity

Cardiovascular complications are major clinical hallmarks of acute and post-acute coronavirus disease 2019 (COVID-19). However, the mechanistic details of SARS-CoV-2 infectivity of endothelial cells remain largely unknown. Here, we demonstrate that the receptor binding domain (RBD) of the SARS-CoV-2...

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Bibliographic Details

Published in:	Cells
Main Authors:	Nader Rahimi, Mitchell R. White, Razie Amraei, Saran Lotfollahzadeh, Chaoshuang Xia, Marek Michalak, Catherine E. Costello, Elke Mühlberger
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Subjects:	COVID-19 SARS-CoV-2 spike protein S-RBD calreticulin intracellular calcium homeostasis
Online Access:	https://www.mdpi.com/2073-4409/12/23/2694