Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion

Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical evolution, leading to death. Their pathogenesis is characterized by conformational changes of the cellular prion protein—PrP<sup>C</...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Amanda Rodrigues Pinto Costa, Marcelly Muxfeldt, Fernanda da Costa Santos Boechat, Maria Cecília Bastos Vieira de Souza, Jerson Lima Silva, Marcela Cristina de Moraes, Luciana Pereira Rangel, Tuane Cristine Ramos Gonçalves Vieira, Pedro Netto Batalha
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	quinone oxoquinoline quinolone scrapie prion
Online Access:	https://www.mdpi.com/1420-3049/27/22/7935