Addition of oh8dG to Cardioplegia Attenuated Myocardial Oxidative Injury through the Inhibition of Sodium Bicarbonate Cotransporter Activity

The biomarker 8-hydroxy-2′-deoxyguanosine (oh8dG) is derived from oxidized nucleic acids or products of oxidant-mediated DNA damage. Enhanced sodium bicarbonate cotransporter (NBC) activity is caused by reactive oxygen species (ROS) production in ventricular myocytes. Thus, we hypothesized that card...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Min Jeong Ji, Kuk Hui Son, Jeong Hee Hong
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	cardioplegia oxidative stress 8-hydroxy-2′-deoxyguanosine sodium bicarbonate cotransporter reperfusion
Online Access:	https://www.mdpi.com/2076-3921/11/9/1641