CPT1A as a potential therapeutic target for lipopolysaccharide-induced acute lung injury in mice

Abstract Acute lung injury (ALI) remains a high mortality rate with dramatic lung inflammation and alveolar epithelial cell death. Although fatty acid β-oxidation (FAO) impairment has been implicated in the pathogenesis of ALI, whether Carnitine palmitoyltransferase 1A (CPT1A), the rate-limiting enz...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Gui-Yun Wang, Xia Xu, Da-Yan Xiong, Lang Deng, Wei Liu, Xiao-Ting Huang
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-01-01
Online Access:	https://doi.org/10.1038/s41598-024-52042-2