Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

The now prevalent Omicron variant and its subvariants/sub-lineages have led to a significant increase in COVID-19 cases and raised serious concerns about increased risk of infectivity, immune evasion, and reinfection. Heparan sulfate (HS), located on the surface of host cells, plays an important rol...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Deling Shi, Changkai Bu, Peng He, Yuefan Song, Jonathan S. Dordick, Robert J. Linhardt, Lianli Chi, Fuming Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	SARS-CoV-2 Omicron spike protein RBD heparin pentosan polysulfate mucopolysaccharide polysulfate
Online Access:	https://www.mdpi.com/1999-4915/14/12/2696