Efficient Identification of Monoclonal Antibodies Against Rift Valley Fever Virus Using High-Throughput Single Lymphocyte Transcriptomics of Immunized Mice

<b>Background</b>: Rift Valley fever virus (RVFV) is a zoonotic virus that poses a significant threat to both livestock and human health and has caused outbreaks in endemic regions. In humans, most patients experience a febrile illness; however, in some patients, RVF disease may result i...

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Bibliographic Details

Published in:	Antibodies
Main Authors:	Ronit Rosenfeld, Ron Alcalay, Yfat Yahalom-Ronen, Sharon Melamed, Avital Sarusi-Portuguez, Tal Noy-Porat, Ofir Israeli, Adi Beth-Din, Ronnie Blecher-Gonen, Theodor Chitlaru, Erez Bar-Haim, Tomer Israely, Anat Zvi, Efi Makdasi
Format:	Article
Language:	English
Published:	MDPI AG 2025-02-01
Subjects:	antibody discovery recombinant antibody single-cell analysis 10x Genomics antibody repertoire profiling Rift Valley fever virus (RVFV)
Online Access:	https://www.mdpi.com/2073-4468/14/1/12