EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

Summary: Drug resistance is the leading problem in non-small-cell lung cancer (NSCLC) therapy. The contribution of histone methylation in mediating malignant phenotypes of NSCLC is well known. However, the role of histone methylation in NSCLC drug-resistance mechanisms remains unclear. Here, our dat...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Qiuyue Zhang, Yajie Shi, Sen Liu, Weiming Yang, Huiping Chen, Ning Guo, Wanyu Sun, Yongshan Zhao, Yuxiang Ren, Yong Ren, Lina Jia, Jingyu Yang, Yi Yun, Guoliang Chen, Lihui Wang, Chunfu Wu
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Subjects:	CP: Cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724000421