Cellular senescence and SASP in tumor progression and therapeutic opportunities

Abstract Cellular senescence (CS), a permanent and irreversible arrest of the cell cycle and proliferation leading to the degeneration of cellular structure and function, has been implicated in various key physiological and pathological processes, particularly in cancer. Initially, CS was recognized...

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Bibliographic Details
Published in:Molecular Cancer
Main Authors: Zening Dong, Yahan Luo, Zhangchen Yuan, Yu Tian, Tianqiang Jin, Feng Xu
Format: Article
Language:English
Published: BMC 2024-08-01
Subjects:
Cellular senescence
SASP
Tumor
Tumor microenvironment
Therapy
Online Access:https://doi.org/10.1186/s12943-024-02096-7

Internet

https://doi.org/10.1186/s12943-024-02096-7

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