Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells

Mast cells are tissue-resident cells that contribute to allergic diseases, among others, due to excessive or inappropriate cellular activation and degranulation. Therapeutic approaches to modulate mast cell activation are urgently needed. Siglec-6 is an immunoreceptor tyrosine-based inhibitory motif...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Cells
المؤلفون الرئيسيون:	Piper A. Robida, Clayton H. Rische, Netali Ben-Baruch Morgenstern, Rethavathi Janarthanam, Yun Cao, Rebecca A. Krier-Burris, Wouter Korver, Alan Xu, Thuy Luu, Julia Schanin, John Leung, Marc E. Rothenberg, Joshua B. Wechsler, Bradford A. Youngblood, Bruce S. Bochner, Jeremy A. O’Sullivan
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2022-03-01
الموضوعات:	mast cell Siglec-6 FcεRI degranulation ITIM endocytosis
الوصول للمادة أونلاين:	https://www.mdpi.com/2073-4409/11/7/1138