A novel oxidative stress- and ferroptosis-related gene prognostic signature for distinguishing cold and hot tumors in colorectal cancer

Oxidative stress and ferroptosis exhibit crosstalk in many types of human diseases, including malignant tumors. We aimed to develop an oxidative stress- and ferroptosis-related gene (OFRG) prognostic signature to predict the prognosis and therapeutic response in patients with colorectal cancer (CRC)...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Xu Wang, Yuanmin Xu, Longfei Dai, Zhen Yu, Ming Wang, Shixin Chan, Rui Sun, Qijun Han, Jiajie Chen, Xiaomin Zuo, Zhenglin Wang, Xianyu Hu, Yang Yang, Hu Zhao, Kongwang Hu, Huabing Zhang, Wei Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	oxidative stress ferroptosis colorectal cancer prognosis tumor microenvironment chemotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1043738/full