Protocol for a randomised controlled trial of ketamine versus ketamine and behavioural activation therapy for adults with treatment-resistant depression in the community

Introduction Although short-term benefits follow parenteral ketamine for treatment-resistant major depressive disorder (TR-MDD), there are challenges that prevent routine use of ketamine by clinicians. These include acute dissociative effects of parenteral ketamine, high relapse rates following keta...

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Bibliographic Details
Published in:BMJ Open
Main Authors: Christopher Frampton, Richard Porter, Greg Murray, Jennifer Jordan, Ben Beaglehole, Paul Glue, Katie Douglas, Cameron James Lacey, Aroha de Bie, Charlie Mentzel, Bridgette Thwaites, Jenni Manuel
Format: Article
Language:English
Published: BMJ Publishing Group 2024-05-01
Online Access:https://bmjopen.bmj.com/content/14/5/e084844.full