Salinomycin causes dedifferentiation via the extracellular signal-regulated kinase (ERK) pathway in rabbit articular chondrocytes

Salinomycin (SAL), a monocarboxylic polyether antibiotic isolated from Streptomyces albus, modulates various cellular responses, including proliferation, apoptosis, and inflammation. However, the effect of SAL on the dedifferentiation of chondrocytes remains unclear. Thus, we investigated the effect...

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Bibliographic Details

Published in:	Journal of Pharmacological Sciences
Main Authors:	Seon-Mi Yu, Song-Ja Kim
Format:	Article
Language:	English
Published:	Elsevier 2015-02-01
Subjects:	Salinomycin (SAL) Extracellular signal-regulated kinase (ERK) Chondrocytes
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861314000309