A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV

Summary: Background: The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb) infection after BCG vaccination are unknown. The mechanism by which BCG influences the tuberculin skin test (TST) remains poorly understood. We evaluated CD4+ T-cell responses in infants exposed to HIV and u...

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发表在:	EBioMedicine
Main Authors:	Alex J. Warr, Christine Anterasian, Javeed A Shah, Stephen C. De Rosa, Felicia K. Nguyen, Elizabeth Maleche-Obimbo, Lisa M. Cranmer, Daniel Matemo, Jerphason Mecha, John Kinuthia, Sylvia M. LaCourse, Grace C. John-Stewart, Thomas R. Hawn
格式:	文件
语言:	英语
出版:	Elsevier 2022-06-01
主题:	Tuberculosis BCG HIV T-Lymphocytes Tuberculin test
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2352396422002079